Evidence, explained.
For your brain.

Articles on brain health, Alzheimer's prevention, genetics, lifestyle medicine, and the science of cognitive longevity — written for patients who want to understand, not just be told what to do.

Alzheimer's Prevention

Early Signs of Alzheimer’s vs. Normal Aging: How to Tell the Difference

Most of us forget where we put our keys. But there is a meaningful difference between normal age-related forgetting and the early changes that signal Alzheimer’s disease. Here is how a preventive neurologist thinks about the distinction — and why recognizing it sooner changes everything.

March 2026 Read →
Biomarkers

Blood Tests for Alzheimer’s Risk: What’s Available Now and What They Mean

For decades, confirming Alzheimer’s pathology required expensive PET imaging or an invasive spinal tap. That is changing. A new generation of blood biomarkers can now detect Alzheimer’s-related brain changes years before symptoms appear — and they are beginning to reach clinical practice.

February 2026 Read →
Genetics & Risk

What Is APOE4, and What Does It Actually Mean for Your Brain?

APOE4 is the single strongest genetic risk factor for Alzheimer’s. Here’s what it is, what it isn’t, and what you can actually do about it.

January 2026 Read →
Lifestyle Medicine

Sleep and Alzheimer’s: What the Research Actually Says

Poor sleep doesn’t just make you tired. It disrupts the brain’s waste clearance system — and the damage accumulates over decades. Here’s what the science says.

December 2025 Read →
Prevention Science

The 45%: What Modifiable Risk Factors Mean for Dementia Prevention

The Lancet Commission found that 40% of dementia cases may be preventable. Here’s what that actually means, and which 14 risk factors are on the list.

November 2025 Read →

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